To the same extent to which our society ages, problems with the memory become more frequent. Be it on account of stress or of higher expectations we or others have of ourselves – more and more people become aware of this complex of problems. And rightly so: impaired memory and presenile dementia influence all aspects of life and not only individual persons. The burden is felt by society as a whole. In the United States alone the annual costs are estimated to be approximately 100 billion dollars.
The older people come to be the less active their brain cells become. What was easy once gets increasingly more difficult. It is estimated that the memory of about half of those older than 50 years is impaired, with disturbances ranging from simply forgetting things to the severe forms of Alzheimer’s disease.
Ginkozin®, a mix of two potent extracts: ginkgo biloba, one of the oldest plants existing on earth, and huperzine A, which is extracted from the moss Huperzia serrata, could prove to be the answer to these problems, though.
Both remedies have been used in China for millennia, and it is mainly huperzine A that in big clinical studies has proven to be very successful in treating disturbed memory and Alzheimer’s disease. Even the renowned medical journal «Journal of the American Medical Association» reported about these investigations.
Ginkgo biloba: ginkgo biloba, an extract from the leaves of the ginkgo tree, which mainly grows in the South and East of the United States and in China, has antioxidative properties and thus protects nerve cells. The active components inhibit the so-called platelet activating factor (PAF), which causes blood platelets to clump. A PAF that is too high damages nerve cells and affects the blood flow to the central nervous system. ginkgo biloba also positively regulates tonus and elasticity of the blood vessels, which in turn leads to a better circulation both in the big vessels and the microvessels.
Huperzine A: huperzine A, an alkaloid from huperzia serrata (a moss which grows in the cool mountain regions of China) has been used in China for millennia to improve memory performance, attention and concentration. The molecular structure of huperzine A (HupA) is well researched. HupA reversibly inhibits acetylcholinesterase (AChE), an enzyme splitting and degrading acetylcholine. Acetylcholine is the messenger substance for the memory functions in the brain and important for our ability to concentrate and be attentive. AChE molecules normally degrade excess acetylcholine and by doing so maintain a balance. In advanced age, under stress and due to toxic influences, however, the acetylcholine levels go down and the delicate balance is disturbed – deficiency symptoms occur which affect our cognitive abilities.
Memory impairments: in clinical and experimental studies huperzine A showed in the test persons a clear improvement of the performance of the brain, an increase in the ability to concentrate and in the spans of attention. The test persons were able to better focus their thoughts and reported a better mental condition.
Alzheimer’s disease: in Alzheimer’s disease, which is characterized by extreme loss of memory and presenile dementia, the most important neurochemical changes are both a marked deficiency in acetylcholine and a reduced synthesis. By inhibiting AChE, the signs and symptoms can be delayed as the degradation of the messenger substance is slowed down.
The efficacy of HupA is due to the fact that it complexes to the acetylcholine molecule exactly at the spot where normally AChE would act. Its half life is longer than that of AChE so that it renders the latter ineffective. Acetylcholine stays intact longer and therefore also acts longer.
The results in the treatment of Alzheimer’s disease were promising, and some researchers believe that the efficacy of HupA is better and that it is safer than all medications that have been sold up to now. In addition, the therapeutic effect lasts longer than that of all other medications.
Depression: first studies showed good results in elderly people suffering from depressive mood who had not reacted to the commonly used antidepressants.
Cardiovascular system / Brain: due to its platelet-inhibiting effect, ginkgo makes the blood «more liquid», so to say and improves circulation. This is true both for arteries and veins. In the brain, the improved flow properties protect the nerve cells, which may have a positive effect on stroke patients.
Tinnitus / Vertigo: ginkgo biloba has a positive influence on these very disturbing and life quality limiting symptoms, also because of its platelet-inhibiting effect. This could be proven in double-blind studies.
Prevention: Ginkozin® can also be taken preventively by healthy people. Especially people of the baby-boom generation who are now around 60 years of age and experience first signs of forgetfulness occasionally can use it as a safe and efficacious «memory booster».
Huperzine A is, so to say, the first line of defense for the nerve cells. Its mechanism of action is basically different from other natural substances supporting the memory functions. It acts directly at the spot where the messenger substances are transferred and helps to provide sufficient quantities of acetylcholine. ginkgo biloba, in turn, plays the role of the «supporting actor» and is a good support and supplement due to its antioxidative and protecting properties.
In Ginkozin® both substances are united at an optimal mutual ratio and therefore enhance the efficacy of each other.
in pharmaceutical grade. Other ingredients: rice flour, magnesium stearate, SiO2.
In normal cases take 1 capsule daily with plenty of fluid.
Regarding the individual substances, ginkgo biloba practically has no serious side effects. In rare cases slight headache and gastric disorders have been reported which, however, last for only one to two days. As yet, no contraindications to intake are known.
Huperzine A is also very safe and well tolerated. However, pregnant and lactating women as well as persons suffering from hypertension and pulmonary problems due to excess bronchial secretion should not take huperzine A.
Up to now all studies showed that Ginkozin® is extremely safe and well tolerated. Cardiovascular problems in the elderly may, however, be a symptom of a serious basic disease and therefore competent and professional advice should be sought (even by healthy people) before self-medication. Store in a cool, dry place and keep out of reach of children.