Coenzyme Q10 is also known under the name of ubiquinone. The name refers to the «ubiquitous» presence of this substance in the human organism and is thus indicative of its special importance for the cell metabolism. It is involved in many vital chemical transformation in the cells, among others in the formation of adenosine triphosphate (ATP), the energy store of the cells.
Coenzyme Q10 is formed in the liver but also ingested with food. It is mainly contained in beef, chicken, mutton, lamb, fish and eggs. In later age the organism no longer produces sufficient quantities of coenzyme Q10. In the course of time this causes a state of deficiency in the body which is responsible for cardiac diseases especially.
Although the reduced coenzyme Q10 content in the blood can be compensated by the intake of a specific diet, eating the necessary food such as beef muscle meat, beef hearts or eggs, is unfortunately also connected with an increased uptake of cholesterol and saturated fatty acids.
As an antioxidant, coenzyme Q10 has greater effects on a cellular level than the better known vitamin E and is the most important of all known coenzymes. It can be found in the cell membrane of the mitochondria where it is responsible for the formation of vital enzymes as well as of the energy storing ATP (adenosine triphosphate). All cells of the body, in particular the muscle cells, and especially the heart muscle with its continuous load, are dependent on a permanent fuel supply. The last important link in this release of energy is, in most cases, the splitting of energy-rich phosphate bonds such as in ATP. If the formation of ATP is disturbed, this can be observed in all cells because it impairs their natural functions. Muscle cells have the greatest need for energy and therefore they have the highest coenzyme Q10 content.
Numerous studies have dealt with the great number of positive effects of coenzyme Q10. To mention just a few examples, there is for instance the better physical exercise tolerance in sports people and also sick people (e. g. those suffering from anaemia).
Another important field of studies were diseases of the cardiovascular system. In this respect, the coenzyme was capable of improving both circulatory disturbances of the heart and cardiac insufficiency due to other reasons. It moreover allowed the heart to work more economically and, as a consequence, also lowered increased blood pressure, if any.
Positive effects were also registered with regard to the quality of sperm, and on various cells of the immune defense. Protection against free radicals, which are produced in greater amounts in the course of infections and inflammatory diseases and also when the body is exposed to contaminants, is another broad field of application, which could also include a slowing of the aging process. Positive effects on the fat and sugar metabolisms are also worth mentioning.
The most important indications result from the effects described and the many functions for which the cells need and use energy:
General well-being / anti-aging: Generally speaking, coenzyme Q10 causes greater functional capacity and improved physical well-being. The coenzyme Q10 levels go down with progressing age, and this could be one of the many causes for aging. Many cell functions are impaired if there is a coenzyme Q10 deficiency and, most important, it gets increasingly difficult to fight cell-damaging free radicals. In animal experiments, at least, life expectancy (in mice) could be prolonged by administrating coenzyme Q10.
Cardiovascular system: It is a proven fact that a deficiency in coenzyme Q10 is also responsible for the development of various cardiovascular diseases. Studies showed that a disturbed blood supply of the coronary vessels (which causes angina pectoris) is positively influenced when coenzyme Q10 is administered. Also in conditions after a cardiac infarction, and in case of chronic cardiac decompensation, insufficient cardiac output due to valvular defects and cardiac irregularities there is an indication to administer coenzyme Q10. In all these clinical pictures studies showed that the complaints and symptoms had improved, that the patients’ physical fitness, their general well-being and life quality had increased. Also in case of hypertension – one important cause for many secondary heart problems – the intake of coenzyme Q10 showed positive effects.
Immune system: Coenzyme Q10 provably supports the immune system on the cellular level, already. Research has shown that coenzyme Q10 supports the formation of cells in the thymus which have defense functions. These T cells are necessary for the cellular immune response, and being killer lymphocytes, they are able to destroy exogenous cells. Moreover, coenzyme Q10 can counteract the retrogression of the thymus usually observed in adults.
Chronic diseases: In chronic diseases of other organs (from Alzheimer’s disease to liver cirrhosis) coenzyme Q10 could at least be tried in support of other measures.
Other areas of indication are disturbances of the sugar and fat metabolisms and chronic inflammation (especially gingivitis).
Also worth mentioning is the well-established application in sports medicine as a supporting administration in athletics.
One capsule contains 30 mg, 60 mg, 100 mg or 200 mg coenzyme Q10 in pharmaceutical grade.
Other ingredients: rice flour, magnesium stearate.
In normal cases depending on your age take with plenty of fluid as follows:
25 – 40 years: from 30 mg daily
40 – 60 years: from 60 mg daily
from 60 years: from 120 mg daily
An ideal synergistic effect can be produced if the product is taken together with carnitine.
No negative side effects have been observed in the treatment with coenzyme Q10. While coenzyme Q10 has no negative effect on other substances, there exist quite a number of medications which considerably reduce the concentration of coenzyme Q10 in the body. Many cholesterol-lowering drugs impair the production of coenzyme Q10 in the body. Should such medication be required, coenzyme Q10 should additionally be taken.
Generally a specialist should be consulted before taking food supplements. This is especially true in cases of chronic disease and regular intake of medication. If the patient experiences symptoms while taking the product, he / she should consult a doctor and inform the doctor of the intake. Store in a cool, dry place and keep out of reach of children.