Basic Facts Effects Indications Composition Dosage Side Effects/Contraindications Instructions
BASIC FACTS
Neurodegenerative diseases are nearly always associated with a slow and insidious reduction of mental fitness and loss of memory and concentration abilities. Currently more than two million persons in Germany are massively impaired by reductions in their mental and psychological abilities. Particularly elderly people are affected by this condition. Due to demographic changes this poses new challenges not only in the political and social sectors, but also for the individual who must learn to cope with loss of memory and a general weakening of cognitive abilities, which may even include depression.
Nearly all cognitive disturbances, if not caused by accidents, tumors or other severe underlying diseases, progress very slowly and insidiously, and are therefore difficult to diagnose at the time of onset of the disease. However, early diagnosis would be important to introduce preventive measures successfully so that mental abilities can be maintained up to an advanced age.
To prevent loss of cognitive abilities, in the field of preventive and modern anti-aging medicine a so-called integrated model for the maintenance of cerebral fitness has proven its worth. This consists of a balanced diet, moderate physical training, special exercises to train one’s mental abilities, and specific forms of meditation. If necessary, specific medications and/or hormones may be used under the supervision of a doctor. However, a program of this type should always be accompanied by high-grade food supplementation so that the missing vitamins and minerals are replaced and active substances from plant extracts are administered in order to achieve positive effects on neuronal structures. Furthermore, one must consider the fact that certain substances have a stimulating effect and should be taken during the day while others have a soothing effect and are better administered in the evening. Thus, one achieves optimal results with a food supplementation program based on chronobiological guidelines to maintain mental fitness and prevent age-related loss of memory.

EFFECTS
Neurochron® is a combination of vitamins, minerals, antioxidants, phospholipids and selected plant extracts. The division into a morning and an evening capsule ensures, for the first time, a balanced combination of natural substances to improve brain function, in keeping with the most recent scientific findings.
The most important constituents for the day are:
Vinpocetine: This active substance is obtained from myrtle seeds. In addition to its anti-oxidative properties it promotes blood circulation in the brain as well as oxygen supply, which stimulates cerebral metabolism. Furthermore, it was shown that the ATP content of nerve cells is increased and thus the brain is provided with the energy required for all of its metabolic processes and functions.
Inositol: Inositol and its derivatives play an important role in the transfer of signals within the cells. For instance, signals that reach the cell from the outside are directed from the cell membrane into the cell nucleus with the help of inositol. Thus, the metabolism of cells is adjusted to external requirements and the cells are stimulated to form specific hormones and other important substances.
Choline and DMAE: Choline belongs to the group of biogenic amines and is present in nearly all life forms. It plays an important role in amino acid metabolism and is involved in the formation of important substances in the body, such as the phospholipid lecithin which is involved in the formation of the cell membrane. Dimethylaminoethanol (DMAE) is also a biogenic amine with similar important functions. Like choline it is involved in the formation of the cell membrane and serves as the basic material for the synthesis of choline. In the body acetylcholine is formed from choline. Acetylcholine is one of the most important neurotransmitters in the body. Particularly in advanced age, the reduction of this messenger substance appears to be the reason for several deficiency symptoms.
Hypericin A inhibits cholinesterase and thus slackens the degeneration of acetylcholine. Furthermore, it prevents depressive moods.
NADH is a substance related to vitamin B3, which is present in all cells and is involved in redox processes. Thus, its most important function is to regulate the energy balance in cells. Reduced levels of this substance were shown to be associated with loss of memory and degenerative symptoms of the brain.
Co-enzyme Q10 and Vitamin E: Both are known to be highly potent antioxidants and act on the cell membrane. Besides, in the respiratory chain co-enzyme Q10 serves as an electron transporter in the mitochondrial cell membrane and is therefore essential for the derivation of energy from cells.
The following substances are especially important for the nocturnal activity of the brain:
Vitamin B1 und B2: They protect the nerve cells by trapping free radicals. Furthermore, vitamin B1 improves cerebral blood circulation while B2 has a positive effect on cell respiration – both of these are essential prerequisites to store information in the long-term memory.
Folic acid and Ginkgo biloba: Folic acid is a co-enzyme involved in several metabolic reactions and is therefore absolutely essential for optimal functioning of the organism. It is particularly significant for differentiated cell growth and the formation of red blood cells which are responsible for oxygen transport. The flavonoids contained in Ginkgo biloba serve as «radical catchers». Ginkgo biloba reduces clumping of blood cells and thus aids in supplying blood to cerebral structures.
Acetyl-L-Carnitine is an ester of the amino acid L-carnitine which, in turn, acts as a transport molecule for fatty acids through the mitochondrial membrane. Acetyl-L-carnitine is metabolized in the mitochondria of cells – a process by which energy is derived for the body’s cellular balance. In addition, it supports the formation of certain neuronal growth factors in specific parts of the brain.
Phosphatidyl serine is an essential component of all cell membranes and plays a significant role in the brain, particularly during the release of neurotransmitters and, consequently, in the transmission of impulses between nerve cells. Its relative deficiency in advanced age is a frequent cause of reduced intellectual performance, poor memory and depressive moods.
Panax ginseng: By its anti-inflammatory effect, anti-oxidative potential and ability to stimulate specific brain receptors it has an anti-depressive effect and enhances intellectual performance.
In addition to this balanced mixture, every capsule contains Bioperine®. This is a standardized extract of black pepper and 98 per cent of it is pure piperine. This active substance improves the absorption of vitamins and enhances the bioavailability of nearly all active substances. Thus, optimal care is ensured.

INDICATIONS
Neurochron® serves to improve brain performance, intellectual abilities and memory, and to enhance concentration abilities in advanced age.
The intake is especially suitable to support preventive measures for degenerative diseases in younger individuals because the degenerative process may already start at the age of 45 years although it may not be immediately detectable in this age group.
COMPOSITION
| AM capsule (morning) |
| |
daily dose
|
mg/100 g
|
|
| Vinpocetine |
15 mg
|
1245
|
|
| Inositol (hexanicotinate) |
30 mg
|
2490
|
|
| Choline (bitrate) |
50 mg
|
4150
|
|
| DMAE |
50 mg
|
4150
|
|
Hypericin A
|
0,4 mg
|
33
|
|
Vitamin E
|
80 mg
|
6640
|
|
| Inositol (6 Phosphate) |
200 mg
|
16600
|
|
| NADH |
2 mg
|
166
|
|
| Q 10 |
10 mg
|
830
|
|
| Bioperine® |
2 mg
|
166
|
|
| |
|
| PM capsule (evening) |
| |
Daily dose
|
mg/100g
|
|
Vitamin B1
|
10 mg
|
830
|
|
| Vitamin B2 |
10 mg
|
830
|
|
| Vitamin B12 |
0,015 mg
|
1,25
|
|
Folic acid
|
0,6 mg
|
50
|
|
| Pantothenic acid |
50 mg
|
4150
|
|
| Ginkgo biloba |
120 mg
|
9960
|
|
| Acetyl-L-Carnitine |
100 mg
|
8300
|
|
| Phosphatidyl serine |
100 mg
|
8300
|
|
| Panax ginseng |
20 mg
|
1660
|
|
| Bioperine® |
2 mg
|
166
|
|
Additional constituents: Dicalcium phosphate, microcrystalline cellulose, stearic acid, magnesium stearate, SiO2
DOSAGE
In normal cases take 1 capsule AM (yellow) in the morning and 1 capsule PM (blue) in the evening with plenty of fluid.
SIDE EFFECTS / CONTRAINDICATIONS
If taken according to the instructions, no contraindications are known in healthy persons. In some cases there may be intolerance reactions (such as nausea) to individual substances contained in Neurochron®. However, these are usually of mild intensity, short duration, and disappear immediately after the treatment is discontinued.
INSTRUCTIONS
Generally a doctor or specialist should be consulted before the intake of food supplements. This is particularly applicable in cases of chronic disease or during regular intake of medication. If you experience symptoms during the intake of Neurochron® you should consult a specialist and inform him/her of the intake of Neurochron®. Keep out of reach of children and store in a cool, dry place.
This product is available at pharmacies or via Pharmatrans Inc.
For information about prices and packing sizes click here. |